Dr Susan Northfield trained as a peptide and medicinal chemist. She completed her PhD in medicinal chemistry from Monash University in 2012, then spent two years in the laboratory of Professor David Craik at The University of Queensland, before returning to Melbourne to join the Drug Design Laboratory in the Department of Pharmacology & Therapeutics (now Department of Biochemistry & Pharmacology) in the School of Biomedical Sciences in 2014. In 2017, Dr Northfield took over as Lab Head, supervising a peptide chemistry program focussed on developing multicyclic peptide mimetics.
Dr Northfield’s research and career opportunities have allowed her to become an internationally recognised researcher in the peptide chemistry field. Susan has spent the last fifteen years working in the fields of medicinal chemistry, chemical biology and structural biology. Across the last five years she has focussed on the development of peptide mimetics of neurotrophins, including BDNF. Peptides made by her lab are mimetics of BDNF loops capable of selectively targeting receptors to replicate BDNF activity, making them useful tools to study receptor function and disease states, including multiple sclerosis.
In 2019, Dr Northfield took on a part-time role managing the ARC Training Centre for Personalised Therapeutics Technologies, while continuing to run her lab. She maintained both roles until March 2022, working with academics, industry and government for the roles. Since April 2022, Dr Northfield has been working full-time as Research Manager in the School of Biomedical Sciences at The University of Melbourne; and holds an honorary fellow position in the Department of Biochemistry & Pharmacology.
Susan has been an active member of the RACI since 2015, initially as a member of Victoria’s Women in Chemistry (WinC) committee and Peptide Users Group (PUG) committee. She was later secretary (2017) and chair (2018) of WinC and treasurer of PUG (2018-2019). She joined the Victorian Branch Committee in 2017, stepping into the secretary role in 2018, and president-elect in 2019. She navigated the Branch through challenging times as president in 2020 – 2022, and in November 2022 took her experience with the RACI into her new role on the RACI National Board.